MediAsha Technologies is a healthcare startup focusing on solving unmet needs and bringing forth novel medical devices. The company has developed its first product ‘InstaSplint’, a first-aid device that immobilizes a fractured limb until the person is taken to the hospital. The splint helps in providing rest to the injured area, preventing further displacement of bone fragments and thus protecting the underlying vessels and nerves from the fracture fragments. MediAsha is a recepient of BIRAC’s Biotechnology Ignition Grant among other awards.
Vidcare Innovations is a startup trying to re-invent how diagnostics are performed by employing microfluidic principles, to develop an equipment-free, over the counter, quantitative immunoassay testing platform technology. The company, in the long run, envisions to empower people to diagnose for various medical conditions at home, with similar easy to use, rapid diagnostic products. Currently, the company is focused on solutions for maternal and child health, with the first offering being a TSH test for screening of hypothyroidism during pregnancy.
Early wound assessment and management is very crucial with the rise in Skin and Soft Tissue Infections (SSTI), ranging from diabetic foot ulcers, surgical site infections, burns, dermatology skin infections etc. Although it was estimated that an ankle is lost to diabetes somewhere in the world every 30 seconds, a more important fact is that up to 85% of all amputations in diabetes should be preventable. Conventional methods of SSTI monitoring are very ineffective. The problem is further compounded in low resource settings due to lack of quality infrastructure. Adiuvo Diagnostics is developing a non-invasive, portable Skin-Scope device to detect, classify major clinically relevant bacteria and fungus causing the infections in real time, and also access the rate of healing within 2 minutes. This will aid the doctors with early and right treatment protocol.
BioPrime AgriSolutions Pvt Ltd is using its pioneering, innovative research & products in the areas of agriculture, horticulture & floriculture. Specifically, they are working on developing technologically advanced, affordable, better products for soil, crop & water management to the farmers, regardless of their farmland size.
The company has been awarded the prestigious Biotechnology Ignition Grant (BIG) from BIRAAC, DBT for developing new solutions in plant breeding. BioPrime’spatented“organo-nano-regulator technology” uses agriculture biologicals to activate/regulate/modulate certain novel targets in plant or pest physiology. Their products combine the precision and rapid action obtained by synthetic/chemical inputs with the goodness of organic products. Their products are aligned with their vision of 100% organic, zero pesticide and zero residue farming.
They are working towards developing a ready-to-use biosurfactant-based formulation, that can successfully aid all household consumers to decontaminate and sanitize their fruits and vegetables before consumption. This unique 100% organic formulation removes 99% of pesticides, chemicals, toxins, pathogens, germs and other lethal substances. Washing of fruits and vegetables in this formulation has been shown to curtail the shrinking of produce and double the shelf life of products even without refrigeration, which can have a huge market in the rural sector, where the over 70 million households have poor access or no access to electricity. The unique selling point of their formulation is that it is odorless, tasteless, non oily, non-sticky, retains natural taste and does not require a rewash step in plain water, which not only helps save water but also simplifies the cleaning process for large-scale cleaning operations at distribution and export centers. This product finds application with farmers for exporting their produce free of any chemicals and pesticides and avoid rejection, at hotels, community centers, consumers etc.
Dee Dee Labs Pvt Ltd, founded in 2016, is a R&D startup company working in the healthcare domain. They are currently working on a non-invasive multigrasp myoelectric prosthetic arm for transradial amputee population in India and the Indian subcontinent. Their bionic arm technology platform is designed to restore anatomical function, lost by amputation, by using intelligent hardware and algorithms that can respond in a human-like way.
Swasti has patented, non toxic, biotechnology products, which empower farmers to mitigate risk caused by crop diseases. They have develop preventive “vaccines” for plants. Swasti’s three pronged program “BioAvert I” gives preventive solutions in the form of blocking pathogen entry, increasing beneficial microbes and stimulating plant defense mechanism. The “HiFarm” services provide advice based on – Hyper spectral imaging, Field analysis techniques, root zone analysis and microscopy.
Use of Swasti products delivers:
- 20 – 40% increase in the yield.
- 2X or more price.
- Reduction in costs (15 – 35%).
- 10 – 100 Times ROI.
Products have been commercialized on over 10,000 acres over 3 years.
WeInnovate Biosolutions Pvt. Ltd is startup whose mission is to develop affordable and rapid healthcare-therapeutic solutions. Currently, they are developing a formulation for accelerated healing of critical wounds. “HealRap” is their novel product for healing of diabetic foot ulcers. They are also involved in development of diagnostic solutions for antimicrobial susceptibility testing within 1 hour. Their mentors include medical doctors, business strategists, pre-clinical and clinical studies advisors, product building experts.
Fluorogent is a spin-off based on NCL’s technology created under Venture Center’s “Lab2Mkt” program. The company wishes to develop fluorescence-based reagents and diagnostic kit useful for quantitative detection of biomarkers such as cysteine and homocysteine, and glutathione (GSH), which play essential roles for regulating the redox balance of many biological processes.
Cysteine is a metabolic product of homocysteine and a precursor of the antioxidant GSH. A deficiency of cysteine leads to diseases such as decreased hematopoiesis (creation of new blood cells), leukocyte loss, psoriasis, slowed growth, liver damage, skin lesions, hair depigmentation, edema, and so on. Elevated levels of homocysterine have been recognized as an independent risk factor for cardiovascular disease. This is also associated with various diseases or clinical conditions, which include Alzheimer’s disease, schizophrenia, end-stage renal disease, osteoporosis, and type II diabetes.
To elucidate the complicated relationship between Cys, Hcy, and GSH and investigate the function of each biothiol in various physiological processes, the simultaneous quantitative detection of these three biothiols is very necessary.
The company has received Biotechnology Ignition Grant by DBT-BIRAC, GoI
Altreal Bioinnovation Pvt Ltd is a spin-off based on CSIR-NCL’s capabilities and created under Lab2Mkt program of Venture Center. The aim of the startup is to develop affordable prostheses for rehabilitation for the Indian healthcare mass market. They are developing explant prosthetics such as nose , ear and eye based on silicone.
The company is a recipient of “Biotechnology Ignition Grant” of DBT-BIRAC, GoI.
Annweshan is a spin-off based on NCL ‘s technology created under Venture Center’s “Lab2Mkt” program. The company wishes to develop innovative health care & biotech products at affordable costs and commercialize these products. Currently Annweshan is working to develop a metabolite (non-nucleic acid) biomarker based novel TB diagnostic kit for sensitive (can detect MTB missed by smear microscopy), specific (to MTB in sputum samples), fast, easy, instrument- free, cheap and point-of-care detection of M. tuberculosis bacilli in patient’s sputum as well as severity of disease in patients. The company has received Biotechnology Ignition Grant by DBT-BIRAC, GoI
Genrich Membranes Pvt. Ltd., a spin-off company based on proprietary technology from CSIR-National Chemical Laboratory, Pune, uses hollow fiber membrane technology to offer cost-effective solutions for O2 enriched sterile air for medical applications (oxygen therapy) for patients suffering from respiratory diseases (asthma, COPD, neonatal, etc.). The developed membrane-based oxygen enrichment unit elevates the amount of O2 in ambient air to only 35%, thus making it a more energy efficient process compared to existing technologies. Moreover, the current OEU is adaptable to diverse applications (rural health centers, hospitals, home care, ambulance, oxygen booths/spas, etc.). In addition, since there is no fouling, these membrane systems can be expected to have a long operational life with minimum maintenance. Genrich membranes has received Biotechnology Ignition Grant by DBT-BIRAC, GoI
Orthocrafts is a spin-off based on NCL ‘s technology created under Venture Center’s “Lab2Mkt” program. The start-up focuses on the development of high molecular weight polylactic acid based bioabsorbable implants. The company will eventually cater to the sports medicine market of India. Orthocrafts has received Biotechnology Ignition Grant by DBT-BIRAC, GoI
Abhiruchi is a spin-off based on NCL ‘s technology created under Venture Center’s “Lab2Mkt” program . The company is working towards demonstrating the proof of concept for a novel formulation (patent protected) comprising a strain of Brevibacterium casei AP9 for a probiotic food additive, which will help reduce cholesterol absorption in the GI tract with potential long lasting action (as seen by higher and faster in-vitro Bile Salt Hydrolase(BSH) production than other LABs and as seen by higher adhesion to mucin layer). Abhiruchi has received Biotechnology Ignition Grant by DBT-BIRAC, GoI
Biolmed is a spin-off based on NCL ‘s technology created under Venture Center’s “Lab2Mkt” program. The start-up aim to develop biomedical products for healthcare applications for human bone defects like bony voids, long bone defects and traumatic /surgical osseous defects. The company’s first product will be a osteoconductive bone graft substitute kit based on the silk-fibroin material. Biolmed has received Biotechnology Ignition Grant by DBT-BIRAC, GoI
VIVIRA is a spin-off based on NCL’s technology. The Start–up plans to develop a novel and patent protected vortex diode based cavitation device (VodCa®) for enhancing bio-gas yield and throughput of anaerobic digesters. In-particular, prove the concept for biological digesters used in distillery industries (enhance throughput per m3 of digester and gas yield per m3 of spent wash by 20%). The technology has applications in several agri- and marine- biotech industries.
ExoCan is the first exosomes based company in India working in the Oncodiagnostic and Therapeutics space. ExoCan is dedicated to build innovative technology platforms in the frontiers of exosomes research by using their propriety technologies. It aims to translate the clinical potential of these tiny vesicles for better management of cancers by employing cross-disciplinary approaches at the forefront of exosomes research. The company is building up a broad range of biofluids e.g. urine, saliva, blood based platforms suitable to end users and clinicians alike. This platforms offer following advantages over existing exosomes based technologies for cancer diagnosis:
1.Rapid, and sensitive method for enriching exosomes from biofluids
2. Enhanced selectivity of the test
3. High yield and precision
4. Choice based use of technology
The company has received Biotechnology Ignition Grant by DBT-BIRAC, GoI, Exocan is founded by Aman Sharma who is persuing his Ph.D from NCCS, Pune
Module is a spin-off based on NCL ‘s technology created under Venture Center’s “Lab2Mkt” program. The start-up is developing affordable and innovative diagnostic devices for rapid microbial detection. The company will leverage the platform technology developed at CSIR-NCL Pune to develope quick, colorimetric, portable and reusable biosensor based on nanofibers for E.coli O157:H7 sensing and detection. The team has already demonstrated reversible thermal chromism and solvent chromism in nanofibers of PCDA/PHBV by doping ZnO nanoparticles and Color change by Biotin-Streptavidin interaction in solution phase. The company has received Biotechnology Ignition Grant by DBT-BIRAC, GoI. They have also been featured at various news media including Economic Times, Times of India and Pixr 8. Module is founded by two engineers Sachin Dubey and usman Khan both of them holding B.Tech and M.tech from University of Rajasthan, Jaipur.
Actorius Innovations and Research Pvt Ltd (AIR) is a research and development company focused on creating novel biomaterials that have critical applications in the life science, drug delivery and medical diagnostics field. The company strives to develop in-house platform technologies that will fulfill a current need in medical procedure by improving upon an existing technology or device, or an unmet need that is clearly defined and acknowledged by medical professionals. AIR is founded by Dr. Jayant Khandare who is an NCL alumnus and Ex-Piramal Life Sciences, Dr. Muralidhara Padigaru who is also an ex-Piramal Life Sciences and Ph.D from PGIMER, Chandigarh. The third co-founder of AIR is Arvindan Vasudevan who has Master’s degree in Chemistry and a Certificate in Business Studies (Marketing).
AIR has received Biotechnology Ignition Grant and Small Business Innovation Research Initiative (SBIRI) grant by DBT-BIRAC, GoI.
Barefeet is a spin-off based on NCL ‘s technology created under Venture Center’s “Lab2Mkt” program. The company is committed to develop the innovative solutions for cheaper, faster and more efficient screening of residual compounds / contaminants in dairy and agro products. BareFeet proposes to screen samples for residual compounds / contaminants using MALDI-MS and to screen multiple analytes per samples at extremely reasonable and affordable costs. The company has received Biotechnology Ignition Grant by DBT-BIRAC, GoI
Seagull Biosolutions is in to immunotherapies & affordable vaccines. The company is working towards building a technology platform for modern, effective, affordable medicines through disruptive vaccine development technology that produces affordable vaccines rapidly. Their proprietary vaccine development platform is called “eSAME” and “Active Virosomes” technologies. Seagull is founded by Dr. Vishwas Joshi who is an alumnus of IISc , Bangalore and ex-Glenmark Pharmaceuticals. The company has received Biotechnology Ignition Grant by DBT-BIRAC, GoI, Grant from Bill & Melinda Gates foundation, raised seed investment and corporate grant.
Nayam innovations is a biomaterial based company working towards developing novel Intra-Ocular Lens (IOL) to provide spectacle-free vision to patients undergoing cataract surgery. The company has received Biotechnology Ignition Grant by DBT-BIRAC, GoI, and raised seed funding through grant and equity investments. Nayam Innovations is founded by Tanuj Gigras who holds a B.Tech and M.Tech in Engineering Physics from IIT Bombay.